Job Identification: 7561

Job Category: Academic

Posting Date: 05/29/2023, 04:21 PM

Apply Before: 07/25/2023, 06:59 AM

Job Schedule Full time

Job Shift: Day

Locations: Hugh Robson Building, Edinburgh, EH8 9XE, GB

Health and Safety Requirements: Key hazards identified (plan is in place)

Criminal Record Check: No criminal record check required

Contract Type: Fixed Term

 

UE07: £36,333.00 - £43,155.00 Per Annum 

College of Medicine and Veterinary Medicine / Edinburgh Medical School / Deanery of Biomedical Sciences / Centre for Discovery Brain Sciences

Full Time: 35 Hours per Week

Fixed Term Contract: 3 years in the first instance

We are looking for a talented researcher to join our team at the UK Dementia Research Institute at the University of Edinburgh, within the lab of Centre Director Professor Giles Hardingham.

 

The Opportunity:

To drive a project aiming to determine how astrocytes change in response to Aß and tau pathology, the role that microglia play in mediating these changes, and the consequences of these changes. Ultimately this will lead to rescue strategies and therapeutic targets to modify patho-progression. The successful candidate will use established in vivo models of ß-amyloidopathy and tauopathy, including genetic models as well as the administration of human brain AD homogenate, plus mice lacking microglia (with and without microglial replacement therapy). Approaches will be tailored to the questions being asked, but may involve single-cell and spatial transcriptomics/proteomics, in vivo optical imaging, PET/MR, behavioural testing, electrophysiology and cell biological/primary culture approaches. All relevant training will be given. For examples of relevant publications see Jiwaji et al (2022) Nature Comm, Baxter et al (2021) Cell Reports, Rojo et al (2019) Nature Comm, Qiu et al (2018) Nature Prot, Hasel et al (2017) Nature Comm. For informal enquiries contact Giles.Hardingham@ed.ac.uk.

 

Your skills and attributes for success:

• A strong track record of research publications commensurate with career stage
• A high level of technical and theoretical knowledge in your current subject area.
• Ambition to develop a project and contribute intellectually to its direction
• Experience in a subset of relevant techniques
• Good interpersonal, time management and team-working skills

 

Click to view a copy of the full job description (opens new browser tab)

 

As a valued member of our team you can expect: 

An exciting, positive, creative, challenging and rewarding place to work. We give you support, nurture your talent and reward success. You will benefit from a competitive reward package and a wide range of staff benefits, which includes a generous holiday entitlement, a defined benefits pension scheme, staff discounts, family friendly initiatives, flexible working and much more. Access our staff benefits page for further information and use our reward calculator to find out the total value of pay and benefits provided.

The University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.

Interviews will be held within 2 weeks of closing date

If invited for interview you will be required to evidence your right to work in the UK.  Further information is available on our right to work webpages.

The University is able to sponsor the employment of international workers in this role. If successful, an international applicant requiring sponsorship to work in the UK will need to satisfy the UK Home Office’s English Language requirements and apply for and secure a Skilled Worker Visa.

Unless stated otherwise the closing time for applications is 11:59pm GMT. If you are applying outside the UK the closing time on our adverts automatically adjusts to your browsers local time zone.

 

ABOUT US

As a world-leading research-intensive University, we are here to address tomorrow’s greatest challenges. Between now and 2030 we will do that with a values-led approach to teaching, research and innovation, and through the strength of our relationships, both locally and globally.

ABOUT THE TEAM

The Edinburgh Medical School: Biomedical Sciences, which is headed by Professor Mike Shipston, employs around 350 staff. Biomedical Sciences hosts the Centre for Discovery Brain Sciences (CDBS, Head: Professor David Wyllie) and Infection Medicine (IM, Head: Professor Juergen Haas). These have strong links with Edinburgh Neuroscience (Head: Prof Siddharthan Chandran) and Edinburgh Infectious Diseases (EID, Head: Professor Ross Fitzgerald). Research themes within Biomedical Sciences include: Genes and Development; Synapses Circuits & Behaviour; Injury & Repair; Signalling, homeostasis & Energy Balance; Ageing & Degeneration; Antimicrobial Resistance; Host-pathogen interactions; Global Health and Diagnostics Research. Our excellence in research is underpinned by the hosting within Biomedical Sciences of the UK Dementia Research Initiative (UKDRI) at Edinburgh (Head: Prof Giles Hardingham) and the Simons Initiative for the Developing Brain (Head: Prof Peter Kind).

Also within Biomedical Sciences is the Biomedical Teaching Organisation (BMTO) which plays a vital role in the administration, coordination and implementation of undergraduate and postgraduate teaching. The BMTO is responsible for the BSc Medical Sciences programme and twelve BSc Biomedical Sciences Honours Programmes. Nineteen Biomedical Sciences courses are delivered to first to third year undergraduates and twenty-six Honours elective courses along with seven Bachelor of Medical Sciences Honours programmes as part of the Bachelor of Medicine & Surgery (MBChB) degree and five BSc Veterinary Sciences Honours Programmes as part of the Bachelor of Veterinary Medicine & Surgery (BVM&S) degree. In addition the BMTO has responsibility for the large portfolio of on-campus and online MSc programmes run by Biomedical Sciences.

Biomedical Sciences is located across a number of sites: the Chancellor’s Building and Queen’s Medical Research Institute at Little France; the Medical School in Teviot Place; the Hugh Robson Building, George Square and No 1 George Square.

In REF2021, the College submitted to three Units of Assessment (UoAs): UoA1 Clinical Medicine, UoA4, Psychology, Psychiatry and Neuroscience, and UoA6 Agriculture, Veterinary & Food Science. Most of the staff in Biomedical Sciences were returned in UoA4 (Neuroscience); this return was ranked 2nd in the UK for “quality” and 3rd in the UK for “power”.  Edinburgh’s submission is the only one in the UK to have been ranked in the top three for both of these descriptors.  Fifty two percent our research papers were awarded the highest score of 4*, defined as world-leading, and a further 38% were rated 3*, defined as internationally excellent.  Moreover, 100% of our ten impact case studies were awarded 4*, meaning they are world-leading in reach and significance and 100% of our environment was awarded 4*, meaning the context in which our research takes place is world-leading in vitality and sustainability.

Biomedical Sciences holds a Bronze Athena SWAN award denoting our commitment to the aims of the Charter, showing that we have recognised and responded to challenges and planned activities for the future.

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