{"id":4215,"date":"2016-05-23T23:26:27","date_gmt":"2016-05-23T13:26:27","guid":{"rendered":"https:\/\/veterinarycareers.com.au\/dev\/?p=4215"},"modified":"2019-02-06T00:22:21","modified_gmt":"2019-02-05T13:22:21","slug":"chronic-pain-treatment-with-stem-cells-arc-centre-of-excellence-for-nanoscale-biophotonics-cnbp","status":"publish","type":"post","link":"https:\/\/veterinarycareers.com.au\/dev\/chronic-pain-treatment-with-stem-cells-arc-centre-of-excellence-for-nanoscale-biophotonics-cnbp\/","title":{"rendered":"Chronic pain treatment with stem cells – ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP)"},"content":{"rendered":"

We had a fantastic Plenary Session at the AVA Conference<\/a> today on the advances in understanding pain by Professor Mark Hutchinson of ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP)…\u00a0<\/em>See this earlier article on the subject. The reference is:\u00a0Australian Life Scientist<\/a><\/p>\n

Chronic pain treatment with stem cells<\/span><\/h3>\n

By Life Scientist Staff Wednesday, 18 May, 2016\u00a039 \u00a022 \u00a09 \u00a00 \u00a02<\/p>\n

The Australian Research Council (ARC) has awarded a Linkage Grant of $340,000 to a research consortium investigating how stem cells can be used to relieve chronic pain.<\/p>\n

The consortium brings together innovative cell labelling technologies developed by the ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP) and a transdisciplinary team of researchers from Macquarie University, the University of Adelaide and regenerative medicine company Regeneus (ASX:RGS).<\/p>\n

CNBP Director Professor Mark Hutchinson has previously demonstrated that neuropathic pain \u2014 pain caused by damage or disease affecting nerves \u2014 is controlled by our immune system. The good news, said Professor Hutchinson, is that stem cells secrete molecules that control or modulate the immune system.<\/p>\n

\u201cBecause neuropathic pain is driven by the immune system, we can use stem cells to control and shut down the pain,\u201d explained Professor Hutchinson, who is based at the University of Adelaide. \u201cHowever, stem cells can secrete both good (anti-inflammatory) and bad (inflammatory) molecules; therefore, the use of cells that secrete the right molecules is going to be critical.\u201d<\/p>\n

With this in mind, CNBP Deputy Director Professor Ewa Goldys and her group at Macquarie University have developed cell labelling technologies to identify and select cells based on the molecules that they are secreting. This technology will be used for the manufacture of stem cells for the treatment of chronic pain.<\/p>\n

\u201cOur efforts will be largely based on utilising CNBP technology, incorporating innovative cell detection, molecular sensing and labelling know-how, operating at the nanoscale level,\u201d Professor Goldys said.<\/p>\n

The study will also build on Professor Hutchinson\u2019s previous work which established that female chronic pain is more widespread than male pain. He noted, \u201cBuilding on our ability to sense what is happening in the body at the cellular and molecular level, this project aims to develop a new understanding of pain as well as its differences related to gender.<\/p>\n

\u201cEstablishing the fundamental mechanism in pain, the role of immune signalling and molecular mediators, we will enable true pain-modifying treatments which address pivotal trigger points in both females and males.\u201d<\/p>\n

Regeneus has patents and patent applications on the use of stem cells for the treatment of neuropathic pain and has had previous success with the use of stem cells for the treatment of neuropathic pain. The outcomes of the research project are expected to lead to the development of allogeneic off-the-shelf stem cell products that have been tailored for the treatment of neuropathic pain in both veterinary and human markets.<\/p>\n

\"\"<\/a><\/p>\n

Image caption: Immune cell responses within the central nervous system in response to chronic pain. Image courtesy of CNBP under CC BY 2.0<\/p>\n

Source: Chronic pain treatment with stem cells<\/a><\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

We had a fantastic Plenary Session at the AVA Conference today on the advances in understanding pain by Professor Mark Hutchinson of ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP)…\u00a0See this earlier article on the subject. The reference is:\u00a0Australian Life Scientist Chronic pain treatment with stem cells By Life Scientist Staff Wednesday, 18 May, 2016\u00a039 […]<\/p>\n","protected":false},"author":7,"featured_media":4219,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[2000],"tags":[142,449,448,150,313],"class_list":["post-4215","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-industry-news","tag-dr-m","tag-nanoscale-biophotonics","tag-pain-management","tag-research","tag-science"],"_links":{"self":[{"href":"https:\/\/veterinarycareers.com.au\/dev\/wp-json\/wp\/v2\/posts\/4215","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/veterinarycareers.com.au\/dev\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/veterinarycareers.com.au\/dev\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/veterinarycareers.com.au\/dev\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/veterinarycareers.com.au\/dev\/wp-json\/wp\/v2\/comments?post=4215"}],"version-history":[{"count":5,"href":"https:\/\/veterinarycareers.com.au\/dev\/wp-json\/wp\/v2\/posts\/4215\/revisions"}],"predecessor-version":[{"id":4222,"href":"https:\/\/veterinarycareers.com.au\/dev\/wp-json\/wp\/v2\/posts\/4215\/revisions\/4222"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/veterinarycareers.com.au\/dev\/wp-json\/wp\/v2\/media\/4219"}],"wp:attachment":[{"href":"https:\/\/veterinarycareers.com.au\/dev\/wp-json\/wp\/v2\/media?parent=4215"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/veterinarycareers.com.au\/dev\/wp-json\/wp\/v2\/categories?post=4215"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/veterinarycareers.com.au\/dev\/wp-json\/wp\/v2\/tags?post=4215"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}